Click the Start menu > Control Panel > Add/Remove Programs > SketchUp #.
To uninstall SketchUp, select uninstall or Modify > Remove. When asked if you'd like to remove SketchUp, click Yes.
If you are having problems with SketchUp, you can try the 'Modify' option, which begins the process of reinstalling the program features that were installed during the last installation. This can fix any application files that were corrupted (this doesn't affect or fix your SketchUp drawing files, the SKP files). If that doesn't work, try uninstalling and reinstalling SketchUp.